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Is it a natural spice/herb or a man made substance?
Interesting question. The answer is yes and no. In fact, the FDA is having issues with foods containing monosodium glutamate labeled as "All Natural"
Here is a great quote about MSG from an article that I will link at the bottom of the page.
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Claiming MSG is natural because free glutamic acid appears in tomatoes is sort of like saying cocaine is natural because it's derived from ingredients found in the coca leaf.
Here is the article:
http://www.newstarget.com/005778.htmlI hope this helps.
Tom